In recent years, there has been a growing interest in the use of phosphodiesterase type 5 (PDE5) inhibitors in the treatment of erectile dysfunction (ED) [,]. The use of PDE5 inhibitors in ED treatment is still considered a controversial issue and has been reported to have some risks and benefits, including an increased risk of cardiovascular events [,]. This is primarily due to the high prevalence of PDE5 inhibitors in the United States, which is the largest country in the world. While the majority of PDE5 inhibitors are associated with an increased risk of cardiovascular disease [, ], the majority of such concerns are related to the risk of sexual dysfunction and the risk of psychological effects [,]. Therefore, in the present study, we aimed to investigate the long-term efficacy and safety of PDE5 inhibitors in the treatment of ED. This study was conducted at the Department of Urology, University of São Paulo, São Paulo, SP, Brazil (SSP) and the National Health System of Brazil (NHS).
The study was conducted at the Department of Urology, University of São Paulo, SSP, Brazil, with the objective of evaluating the long-term efficacy and safety of PDE5 inhibitors in the treatment of ED. The study was approved by the Institutional Review Board (IRB) of the University of São Paulo. The participants were men aged 18–70 years with a mean age of 55.7 years (SD ± 12.8 years) and a median of 55.7 years (range: 35–89 years), who were taking at least two PDE5 inhibitors. All participants received a standardized medical history and physical examination at the time of study. The patients were evaluated for ED and their ED symptoms and the signs and symptoms of ED (Viagra®, Cialis®, and Viagra®) were recorded. Patients were also asked to report any sexual symptoms or signs of ED. The patients were randomly allocated to one of two treatment groups: the PDE5 inhibitor PDE5 inhibitor group (n = 30) and the control group (n = 30). Patients were randomly assigned to one of the following groups: the control group received the same PDE5 inhibitor (n = 30) and the control group received a placebo. The mean age of the patients was 51.6 years (SD ± 8.6 years) and 53.7 years (SD ± 8.3 years) in the PDE5 inhibitor group and 53.8 years (SD ± 8.3 years) and 59.1 years (SD ± 7.6 years) and 60.7 years (SD ± 7.2 years) and 61.3 years (SD ± 7.2 years) in the control group. The patients in both groups were asymptomatic at the time of study, with a mean International Index of Erectile Function (IIEF) score of 5.3 (range: 4–10) and a mean IIEF score of 5.4 (range: 4–8) at the start of the study. The patients were asymptomatic at the time of study and completed the study. The participants in both groups were asymptomatic with no history of ED, but had frequent or frequent erectile dysfunction (Viagra® or Cialis®).
The patients were randomly assigned to receive one of the following treatment groups: PDE5 inhibitor group (n = 30) and control group (n = 30). The mean age of the patients in both groups was 47.6 ± 6.4 years (SD ± 6.7 years) in the PDE5 inhibitor group and 47.8 ± 6.5 years (SD ± 5.6 years) and 53.7 ± 6.9 years (SD ± 5.9 years) and 59.1 ± 6.2 years (SD ± 7.1 years) and 63.1 ± 6.4 years and 63.9 ± 6.8 years and 60.7 ± 5.5 years and 61.3 ± 5.3 years and 61.3 ± 6.5 years and 61.3 ± 6.5 years and 60.7 ± 5.3 years and 60.7 ± 5.5 years and 60.7 ± 5.5 years and 63.1 ± 5.3 years and 63.9 ± 5.3 years and 63.9 ± 5.3 years and 63.9 ± 6.3 years and 63.9 ± 6.5 years and 60.7 ± 5.5 years and 60.7 ± 5.5 years and 60.7 ± 5.5 years and 60.7 ± 6.5 years and 60.7 ± 6.5 years and 60.7 ± 6.5 years and 60.7 ± 6.5 years and 60.7 ± 6.5 years and 60.
Viagra Connect is a new erectile dysfunction treatment which does not require a prescription.
The first of its kind, Viagra Connect is a safe and discreet over-the-counter medication that can legally be bought online without a trip to your doctor.
We need to ensure that this medicine is suitable for the person it is intended for. Therefore, it should only be purchased by the person taking it.
A pharmacist may need to contact you by phone before providing the product. If they cannot reach you within 72 hours, your order may be delayed, or this item may be cancelled from your order.
Please ensure your contact details are correct before ordering this medicine.Suitable forViagra Connect is for men 18 years and older who have difficulty getting and/or keeping an erection hard enough for sex
Age RestrictionYou must be at least 18 years old to purchase this product.
Directions for use:Please read the enclosed leaflet carefully before use.
• take 1 tablet approximately one hour before sexual activity• swallow tablet whole with water• do not take more than 1 tablet a dayViagra Connect starts to work within 30-60 minutes. You may take it up to 4 hours before sexual activity.
Hazards and Cautions
Do NOT take if you:
Talk to your pharmacist or doctor before taking if you:
As with all medicines, please ensure you read the patient information leaflet before taking this item.
VIAGRA CONNECT is based off of your medical history, which can be different than with any other item. This medicine does not affect your ability to have sex, as it is not intended to. If you need to take it, your doctor should advise you how.VIAGRA CONNECT is not intended for use in women or children. However, it may be prescribed to you by a doctor for this use. Please tell your doctor before using this medicine.
do not take if you:
Do not have an erection problem
Please complete theAlways posted patient information Lancet Viatris 2017;8:4943-59 Please read the patient information before you start taking VIAGRA CONNECT. If you have any future concerns, please read it carefully.Talk to your doctor or pharmacist before taking VIAGRA CONNECT if you have any underlying health conditions, as VIAGRA CONNECT is not intended to be a substitute for professional medical advice, diagnosis or treatment.VIAGRA CONNECT is based off of the medical history and you also have the companionSuitable for usemedical expeltion webinars; ask your doctor if VIAGRA CONNECT is right for you.There is no direct link between VIAGRA CONNECT and breast cancer. VIAGRA CONNECT is not intended to be a substitute for professional medical advice, diagnosis or treatment. Talk to your doctor before taking VIAGRA CONNECT.Fast delivery from a licensed UK pharmacy. We offer discreet, we offer discreet, we offer discreet, fast delivery from a licensed UK pharmacy. We offer discreet, we offer discreet, we offer discreet, we offer discreet, we offer discreet, we offer discreet. We offer discreet, we offer discreet, we offer discreet, we offer discreet, we offer discreet, we offer discreet, we offer discreet, fast delivery. We offer discreet, sildenafil free delivery
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Sildenafil is used to treat erectile dysfunction (ED) in men. It is important to note that sildenafil should only be obtained from a licensed UK pharmacy.
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